Calculation question for ED50, Dose-ratio, and Kaff based on dose response data for acetylcholine in the absence and presence of atropine. Data is taken from isolated guinea pig ileum in vitro .The question has 3 parts: Part one requires calculation of ED50 based on given data; Part two requires calculation of the dose-ratio and part three calculation of Kaff for atropine. Useful feedback is given throughout.
https://virtualpharmacologylab.com/resources/assets/GPI/swf/ED50_PLOT_02.swf
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Guinea-Pig Ileum
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Sheffield BioScience Programs