This is a two part question. The first part of a calculation question on affinity constant for acetylcholine in guinea pig ileum. Users are provided with a set of data for the response of the ileum to different bath concentrations of acetylcholine and another set of data for the response in the presence of a known concentration of a reversible competitive antagonist (atropine). This poart of the calculation asks the user to submit an answer for the dose ratio i.e. the concentrations of acetylcholine producing the same response from each set of data - these terms are explained in the question. Feedback is provided for incorrect answers. The second part requires calculation of the affinity constant using the previously calculated dose ratio. Again helpful feedback is given.
https://virtualpharmacologylab.com/resources/assets/GPI/swf/FREE_04.swf
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Guinea-Pig Ileum
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Sheffield BioScience Programs