Determination of standard dose for acetylcholine and histamine and effects of antagonists in guinea pig ileum


Determination of standard dose (a dose which produces a sub-maximal (75%) response for acetylcholine and histamine in guinea pig ileum. Once determined the effects of antagonists mepyramine and atropine are investigated. Students must complete calculations based on the data provided (standard dose) and answer self-assessment questions about the observed effects of the antagonists.


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CAL Package

Guinea-Pig Ileum